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KMID : 0367419790200080061
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Journal of Korean Pediatric Society
1979 Volume.20 No. 8 p.61 ~ p.66
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Four Cases of Anencephaly with Multiple Anomalies
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高祥昊/Ko, Sang Ho
金喜大/李秀雄/申相滿/安昌一/睦楨銀/梁文浩/Kim, Whi Dai/Lee, Soo Woong/Shin, Sang Man/Ahn, Chang Il/Mok, Jung Eun/Yang, Moon Ho
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Abstract
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The incidence of anencephaly ranges from 0. 1 to 6.7 per 1, 000 births. Female fetuses predominate, especially among prematures, with a ratio of between 3 and 7 to 1.
The infants are either stillborn or die within a few days of birth. By about 23 days´ gestational age the neural tube is complete, except for an opening at each end, the anterior and posterior neuropores. Failure of closure of the anterior neuropore causes anencephaly.
Ultrasound scanning of the skull in the anencephalic fetus, measurement of alpha-fetoprotein content in amniotic fluid may also be of help in intrauterine diagnosis.
Four cases of anencephaly with multiple anomalies experienced at nursery of Kyuug Hee University Hospital were reported with brief review of related literatures.
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